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Table of contents Important framing: what "dose" means for an investigational drug Dose ranges tested in published trials Why 2.4 mg became the focus dose The titration schedule used in trials Injection technique and frequency Why dose-response flattens at higher doses How CagriSema combines cagrilintide and semaglutide dosing The gray-market dosing problem The contrary view: dose may differ in commercial labeling Decision framework for patients considering trials FAQ Sources Important framing: what "dose" means for an investigational drug This article describes doses studied in clinical trials